Cafepharma merck - ctff.bne-dev.de Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. NOXXON Pharma AG (Berlin, Germany) based on one of the biggest and best protected patent portfolios in the industry, Berlin-based NOXXON Pharma AG develops biostable aptamers, novel substances based on mirror image nucleic acids. Global Markets Directs, Santaris Pharma A/S - Product Pipeline Review - 2014, provides an overview of the Santaris Pharma A/Ss pharmaceutical research and development focus. These so-called Spiegelmers (the German word Spiegel means mirror) are highly specific for the pharmacologically relevant target for which they were selected. [2] Created by a merger between Cureon and Pantheco, Santaris developed RNA-targeted medicines using a Locked Nucleic Acid (LNA) Drug Platform and Drug Development Engine. By using its proprietary Locked Nucleic Acid (:LNA) platform and tissue-targeting expertise, Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or . Name of the organization that made the acquisition, Total amount raised across all funding rounds, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Descriptive keyword for an Organization (e.g. Cafepharma best companies - itnnkb.urlaub-an-der-saar.de Santaris Pharma A/S Advances miravirsen, the First microRNA - NATAP Santaris' pipeline of RNAi - or ' gene silencing ' - drugs are based on its Locked Nucleic Acid (LNA) platform and its lead candidate is miravirasen, a novel hepatitis C treatment in phase II trials. Merck's stock went from $48 at the end of 2014 to $90 at the end of 2019, representing a change of 87.5%. Such drugs have the potential to transform the field of RNA-targeted therapeutics, making specific and effective gene silencing a reality in human medicine. Santaris Pharma A/S Advances a Second Drug from Its. Zealand PharmaDenmarkListedZealand Pharma is a biotechnology company focused on the discovery, design and development of innovative peptide-based medicines. - The report provides brief overview of Santaris Pharma A/S including business description, key information and facts, and its locations and subsidiaries, - The report reviews current pipeline of Santaris Pharma A/Ss human therapeutic division and enlists all their major and minor projects, - The report features product description and descriptive mechanism of action for key pipeline products along with the products developmental history and major milestones, - Special feature on out-licensed and partnered product portfolio, - The report summarizes all the dormant and discontinued pipeline projects, - Latest news and deals relating to the Santaris Pharma A/Ss pipeline products, - Evaluate Santaris Pharma A/Ss strategic position with total access to detailed information on its product pipeline, - Assess the growth potential of Santaris Pharma A/S in its therapy areas of focus, - Identify new drug targets and therapeutic classes in the Santaris Pharma A/Ss R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas, - Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps, - Develop strategic initiatives by understanding the focus areas of Santaris Pharma A/S and exploit collaboration and partnership opportunities, - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage, - Plan mergers and acquisitions effectively by identifying the most promising pipeline of Santaris Pharma A/S, - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope, - Explore the dormant and discontinued projects of Santaris Pharma A/S and identify potential opportunities in those areas, - Avoid Intellectual Property Rights related issues, Pharma Pipeline Review - Market Research Reports, Santaris Pharma A/S - Product Pipeline Review - 2014. Roche to acquire Santaris Pharma to expand discovery and development of Contact us at the Consulting WP office nearest to you or submit a business inquiry online. The method may offer new hope to allergy sufferers everywhere because it targets the source of the allergic reaction rather than the symptoms.This is achieved by eliminating IgE, an antibody causing the release of histamine which triggers the allergic reactions for many individuals. Santaris Pharma is a privately owned, clinical-stage biopharmaceutical company focused on developing a novel class of antisense drugs, termed LNA, intended to . SANTARIS PHARMA - New data show breakthrough microRNA-targeted therapy Resistentia Pharmaceuticals AB, a biotechnology company founded in 1998, developing an allergy vaccine with human as well as veterinary applications. Santaris Pharma was acquired by Roche in 2014 for $450M. Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or activity of select RNA targets to address diseases that are difficult-to-treat with . Santaris Pharma A/S Raises EUR 40 Million Of New Equity The core therapeutic focus of our company is obesity, Type II diabetes / metabolic syndrome, inflammatory diseases, and organ protection in severe cardiovascular diseases such as myocardial infarction and post-surgical organ failure. santaris pharma a/s has a robust product pipeline based on its proprietary lna technology including mrna and microrna drug discovery and development partnerships and collaborations with shire (rare genetic disorders), wyeth, now part of pfizer, (delivery of lead candidates against up to ten targets), glaxosmithkline (four viral disease drug Eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. cafepharma best companies Request Profile Update Roche pays $450m for 'gene-silencing' firm Santaris Pharma Santaris Pharma discovers and develops RNA-targeted therapies to treat infectious diseases and metabolic disorders. Santaris Pharma - Wikipedia Roche has just announced a $450m deal to acquire Danish company Santaris Pharma, a specialist in a form of antisense therapy that switches off a gene by interacting with messenger RNA (mRNA) to. Directory of Companies. Pipeline Update on Santarus Candidate - finance.yahoo.com Arexis uses forward genetics for a high-resolution molecular dissection of causative disease mechanisms. Phase 1 clinical study to assess safety and tolerability of SPC4955, a drug inhibiting synthesis of apolipoprotein B (apoB), a major protein component involved in the . in addition to miravirsen, santaris pharma a/s has a robust product pipeline targeting mrnas and micrornas both internally as well as in partnerships and collaborations with miragen therapeutics (cardiovascular diseases), shire plc (rare genetic disorders), pfizer (undisclosed therapeutic areas), glaxosmithkline (viral disease) and enzon Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam. Our pipeline is focused on gastrointestinal, metabolic and other specialty diseases where we believe that the present standard of care is inadequate and where we have the resources to advance our peptide-based product candidates into the later stages of clinical development, including registration and commercialization, while opportunistically considering partnership relationships that may arise. Santaris Pharma is using LNA to make novel, highly potent and stable RNA Antagonists. PDF. Ascendis Pharma: We've got making a difference for patients down to a +45 4517 9888 hs@santaris.com Back to news Through its partnerships with pharmaceutical companies, Santaris covers a range of therapeutic areas including cancer, cardiovascular disease, infectious and inflammatory diseases, and rare genetic disorders. Roche Innovation Center Copenhagen is the home of RNA Molecule Research, an integrated part of Roche Pharma Research and Early Development. Associated sectors: Pharmaceuticals; Life sciences; Life Sciences - Pharma; Biotech; Life Science; Biotechnology; Healthcare - Drug development; Biopharmaceuticals; Healthtech; Healthcare; Life Sciences Companies - Drug Discovery and Development; Action PharmaDenmarkAcquiredAction Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. Products on the veterinary market includes the adjuvant for the leading horse influenza vaccine. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. MedChemComm View Article Online Published on 01 August 2014. CiVi's innovative pipeline includes CIVI 007, a long-acting PCSK9 third-generation Locked Nucleic Acid antisense molecule being developed for the treatment of cardiovascular disease. Santaris Pharma AS - Pharmaceuticals & Healthcare - Deals and Alliances Profile Published by GlobalData at researchbeam.com [Report Price $250] 29 Pages help@researchbeam.com +1-971-202-1575 | Toll Free: +1 (800)910-6452 Privacy Policy Zealand Pharma is a biotechnology company focused on the discovery, design and development of innovative peptide-based medicines. [2] Created by a merger between Cureon and Pantheco, Santaris developed RNA-targeted medicines using a Locked Nucleic Acid (LNA) Drug Platform and Drug Development Engine. Santaris Pharma A/Swas a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. COPENHAGEN, Denmark | November 10, 2008 | Santaris Pharma announced today that SPC3042, a RNA-based antisense oligonucleotide developed using the company's proprietary Locked Nucleic Acid (LNA) technology, potently blocks survivin, a key survival protein in cancer cells, in both in vitro and in vivo models of prostate cancer. Description Source: VentureRadar Research / Company Website. LinkedIn The vaccine would be safer, easier to administer and more cost effective than other potential drug candidates currently under development. In addition to miravirsen, Santaris Pharma A/S has a robust product pipeline targeting mRNAs and microRNAs both internally as well as in partnerships and collaborations with miRagen Therapeutics . Santaris Pharma A/S advances a second drug from its cardiometabolic program, SPC4955, inhibiting apoB, into Phase 1 clinical trials for the treatment of high cholesterol. Founded in 2003 Acquired "Santaris Pharma A/S is a clinical stage biopharmaceutical company developing next generation RNA-silencing drugs for the treatment of cancer and metabolic diseases. WhatsApp acquired by Facebook). Refresh Roche Bags Santaris Pharma A/S In Deal Worth $450 Million Santaris Pharma - Company, Denmark - SWFI We are currently in Phase 1/2 trials with our epigenetic drug, SP-2577, and in IND-enabling studies with SP-3164, a targeted protein degrader. It is designed to target the viral mRNA and therefore provides for low off-target effects. Santaris Pharma is a biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. Home - Salarius Santaris Pharma A/S was a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. Santaris, a privately held biopharmaceutical company based near Copenhagen, Denmark, has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. The top players in pharma know how to adapt. Forbion Announces Sale of Portfolio Company, Santaris Pharma, to Roche For further information, please contact Santaris Pharma: Dr Keith McCullagh, President & CEO, Santaris Pharma A/S, Copenhagen, Denmark. Santaris Pharma A/S Advances miravirsen, the First microRNA-Targeted Isis Pharmaceuticals, Inc. v. Santaris Pharma A/S Corp. The companys research and development activities focus on infectious diseases and cardiometabolic disorders, while partnerships with major pharmaceutical companies include a range of therapeutic areas including cancer, cardiovascular disease, infectious and inflammatory diseases, and rare genetic disorders. Roche to Acquire Santaris Pharma to Expand RNA Portfolio - Yahoo! This site 2022 Antares Pharma. The popularity score combines profile views, clicks and the number of times the company appears in search results. Veloxis Pharmaceuticals, Inc. Initiates Phase 1 Study of ART-123 in the U.S. and Japan. Antisense oligonucleotides: modifications and clinical trials Roche | Pharma R&D - Copenhagen, Denmark - Santaris Pharma The core therapeutic focus of our company is obesity, Type II diabetes / metabolic syndrome, inflammatory diseases, and organ protection in severe cardiovascular diseases such as . Responsibility for Product Development including Toxicology, Clinical Operations, Medical Affairs, Regulatory Affairs, QA and Project Management . Santaris Pharma unveiled its newest microRNA therapeutic program this week having acquired intellectual property from Massachusetts General Hospital related to the use of miR-33 as a target for cardiovascular disorders including hypercholesterolemia. Data from a phase II study has been published as well [96]. Arexis ABSwedenAcquiredArexis AB, founded by experienced scientists in 1999, is a drug discovery and development company focusing on metabolic and inflammatory diseases. Tel. Thanks to their structural characteristics, Spiegelmers are extremely resistant to degradation and not immunogenic a new generation of improved therapeutics. The core therapeutic focus of our company is obesity, Type II diabetes / metabolic syndrome, inflammatory diseases, and organ protection in severe cardiovascular diseases such as myocardial infarction and post-surgical organ failure. PDF. Patent number: 8906871. All Rights Reserved. The company has strategic partnerships with miRagen Therapeutics, Shire PLC, Pfizer, GlaxoSmithKline, and Enzon Pharmaceuticals. By continuing, you agree to VentureRadar's. Roche re-enters RNAi space with $250m Santaris acquisition july 27, 2006 announced agreement with enzon pharmaceuticals, inc. plaintiff alleges santaris "sold two antisense gapmer molecules and targets to enzon for $6 million," ( id. 46), and that, pursuant to the agreement, "enzon nominated six additional targets for which santaris agreed to identify lna gapmer compounds that inhibit the nominated - Santaris Pharma A/S initiates Phase 2a clinical trial with miravirsen (SPC3649) to assess safety and tolerability in treatment-naive patients with chronic Hepatitis CHOERSHOLM, Denmark and SAN Santaris advances a second drug from its cardiometabolic programme Santaris Pharma A/S Advances miravirsen, the First microRNA-Targeted Dog kom selskabet i gr med en opdateret pipeline Hanne Damgaard Jensen synes godt om dette . Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. Discover our pipeline . The Roche Innovation Center in Copenhagen, originating from the acquisition of Santaris Pharma in 2014, is a leader in the rapidly emerging field of RNA-targeted drugs. The company, which was created in May 2003 through the merger of Cureon A/S and Pantheco A/S, owns the exclusive worldwide rights to the use of locked-nucleic acids (LNA) in pharmaceuticals. Santaris Pharma A/S - Product Pipeline Review - 2014 Published by Global Markets Direct at researchbeam.com [Report Price $1500] 39 Pages help@researchbeam.com +1-971-202-1575 | Toll Free: +1 (800)910-6452 By using its proprietary Locked Nucleic Acid (:LNA) platform and tissue-targeting expertise, Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or activity of select RNA targets to address diseases which . You must have cookies enabled to login Danish Therapeutics company focused on antibody-drug conjugates (ADCs) for the treatment of cancers. Thanks to their structural characteristics, Spiegelmers are extremely resistant to degradation and not immunogenic a new generation of improved therapeutics. Formerly known as SPC2968, the drug now called RG6061 was previously under development with Enzon Pharmaceuticals, but Santaris regained full ownership of the compound last year when that partnership ended. Genentech Pipeline. Santaris Pharma - Funding, Financials, Valuation & Investors [3] Terms and Conditions Contact Email info@santaris.com Phone Number (454)517-9800 Santaris Pharma A/S is a privately held clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. A pipeline with the potential to impact patient lives worldwide. About Santaris Pharma. Our pipeline is focused on gastrointestinal, metabolic and other specialty diseases where we believe that the present standard of care is inadequate and where we have the resources to advance our peptide-based product candidates into the later stages of clinical development, including registration and commercialization, while opportunistically considering partnership relationships that may arise. Downloaded by University of Colorado at Boulder on 06/07/2015 23:37:18. REVIEW View Journal | View Issue Antisense oligonucleotides: modications and clinical trials Cite this: Med. Submit a Company Swiss Therapeutics company developing therapies to treat severe neurological disorders. Stephen Rubino, PhD, MBA en LinkedIn: Sporos BioDiscovery Presents . This report provides comprehensive information on the current therapeutic developmental pipeline of Santaris Pharma A/Ss, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. capabilities to rapidly deliver potent single-stranded LNA-based drug candidates across a multitude of disease states. The method may offer new hope to allergy sufferers everywhere because it targets the source of the allergic reaction rather than the symptoms.This is achieved by eliminating IgE, an antibody causing the release of histamine which triggers the allergic reactions for many individuals. The core therapeutic Resistentia Pharmaceuticals AB, a biotechnology company founded in 1998, developing an allergy vaccine with human as well as veterinary applications. Roche to Acquire Santaris Pharma to Expand RNA Portfolio - Yahoo! Santarus initiated a phase IIb study on its pipeline candidate, SAN-300. HYB_fib (dcRNA) The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. About Antares; Medicines; For Partners; For Investors; For Patients; Careers; Contact Us Seed, Series A, Private Equity), Whether an Organization is for profit or non-profit, General contact email for the organization, Auto-generated name of transaction (e.g. Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. In addition to miravirsen, Santaris Pharma A/S has a robust product pipeline targeting mRNAs and microRNAs both internally as well as in partnerships and collaborations with . Alliance strengthens both Companies' oncology pipelines. Our technologies have the potential to work in both liquid and solid tumors. The Company is biology-driven with proprietary technology and a strong focus on product development. Santaris Pharma 2007 - 2009 2 r. Roche (SIX: RO, ROG; OTCQX: RHHBY) has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. - Santaris Pharma A/S initiates Phase 2a clinical trial with miravirsen (SPC3649) to assess safety and tolerability in treatment-naive patients with chronic Hepatitis C . Roche to acquire Santaris Pharma to expand discovery and development of This new class of medicines has the potential to address difficult to treat diseases in a range of therapeutic areas. You can follow this company for updates by clicking here. CARY, N.C., U.S.A. (March 28, 2022) - Veloxis Pharmaceuticals, Inc., an Asahi Kasei company, today announced initiation of study drug dosing in ART-123.PN101, a phase 1 study designed primarily to assess the safety and tolerability of ART-123 (thrombomodulin . Active, Closed, Last funding round type (e.g. Santaris Pharma A/S is a clinical- stage biopharmaceutical company focussed on developing next generation RNA-silencing drugs based on its proprietary LNA ( Locked Nucleic Acid ) technology for the treatment of cancer , metabolic diseases and gentic disorders. Enzon and Santaris Pharma Enter into Global Collaboration Date of Patent: December 9, 2014. - The loss after tax realised in the 2nd quarter of 2009 was 21,6m DKK (2,9m EUR) compared to 29,8m DKK (4,0m EUR) in the 2nd quarter of 2008. Abstract: The present invention relates to very short heavily modified oligonucleotides which target and inhibit microRNAs in vivo, and their use in medicaments and pharmaceutical compositions. Hybridize Therapeutics Since Gilde invested in Santaris Pharma, the company has advanced its product pipeline through the clinic and signed commercial collaboration agreements with GlaxoSmithKline, Pfizer, Bristol-Myers Squibb, Roche and Shire. [1] The company also had a branch in San Diego, California that opened in 2009. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects. Yesterday, Roche paid $250m - plus a potential $200m more in milestone payments - to buy Copenhagen, Denmark-based biotech Santaris (owned in part by private equity firms Forbion Capital Partners and Seventure Partners) in a deal that adds three RNA-targeted therapies to its pipeline as well as the proprietary microRNA Locked Nucleic Acid . Acute & chronic kidney injury We focus on a very specific protein (undisclosed) that plays a major role in inflammation / fibrosis. HCV Awareness: Santaris Pharma A/S Advances miravirsen, the First Efficacy studies in HCV infected chimpanzee with 12 weekly intravenous dosing with miravirsen found a marked and lasting decline of the viral titer [95]. 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Santaris Pharma - Gilde Healthcare We have three endocrinology rare disease product candidates in clinical development, and a pipeline of oncology candidates closely following. BASEL, Switzerland I August 4, 2014 I Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. About Santaris Pharma Sample Clauses | Law Insider
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